研究業績

2024年

学術論文

• "Investigating screw-agitator speed ratio impact on feeding performance in pharmaceutical manufacturing using discrete element method"
  Luz Nadiezda Naranjo Gómez, Kensaku Matsunami, Paul Van Liedekerke, Thomas De Beer, Ashish Kumar
  Scientific Reports 14, 21234 (2024).

  • URL
  • DOI: 10.1038/s41598-024-72288-0
• "Hybrid modeling of T-shaped partial least squares regression and transfer learning for formulation and manufacturing process development of new drug products"
  Keita Yaginuma, Kensaku Matsunami, Laure Descamps, Alexander Ryckaert, Thomas De Beer
  International Journal of Pharmaceutics 662, 124463 (2024).

  • URL
  • DOI: 10.1016/j.ijpharm.2024.124463
• "Roles of mechanistic, data-driven, and hybrid modeling approaches for pharmaceutical process design and operation"
  Mohamed Rami Gaddem, Junu Kim, Kensaku Matsunami, Yusuke Hayashi, Sara Badr, Hirokazu Sugiyama
  Current Opinion in Chemical Engineering 44, 101019 (2024).

  • URL
  • DOI: 10.1016/j.coche.2024.101019
• "Scenario Analysis of Vaccine Supply for COVID-19 in Japan Using Mathematical Models of Infectious Diseases"
  Junu Kim, Kensaku Matsunami, Yusuke Ichida, Kozue Okamura, Sara Badr, Hirokazu Sugiyama
  Journal of Chemical Engineering of Japan 57, 1, 2313318 (2024).

  • URL
  • DOI: 10.1080/00219592.2024.2313318
• "Analysis of the effect of formulation properties and process parameters on granule formation in twin-screw wet granulation"
  Michiel Peeters, Ana Alejandra Barrera Jiménez, Kensaku Matsunami, Michael Ghijs, Eduardo Dos Santos Schultz, Mina Roudgar, Tamas Vigh, Fanny Stauffer, Ingmar Nopens, Thomas De Beer
  International Journal of Pharmaceutics 650, 123671 (2024).

  • URL
  • DOI: 10.1016/j.ijpharm.2023.123671

国際学会

• "In-Depth Understanding of the Impact of Material Properties on the Performance of Jet Milling of Active Pharmaceutical Ingredients"
  (Oral) 〇Kensaku Matsunami, Viktor Bultereys, Laure Descamps, Ashish Kumar
  2024 AIChE Annual Meeting, 27–31 October 2024, San Diego Convention Center/Hilton San Diego Bayfront, San Diego, USA (2024).
• "Development of Robust Design Space for Integrated Pharmaceutical Processes through Uncertainty Analysis"
  (Oral) 〇Kensaku Matsunami, Zoltan K. Nagy
  2024 AIChE Annual Meeting, 27–31 October 2024, San Diego Convention Center/Hilton San Diego Bayfront, San Diego, USA (2024).
• "Mechanistic and data-driven models for tablet dissolution to identify key parameters in continuous direct compression"
  (Poster) 〇Kensaku Matsunami, Alexander Ryckaert, Remco Mariën, Bram Bekaert, Valérie Vanhoorne, Thomas De Beer, Chris Vervaet, Ashish Kumar
  14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18–21 March 2024, Austria Center Vienna, Vienna, Austria (2024).
• "Novel approach integrated T-shaped partial least squares regression and transfer learning for tableting scale up"
  (Poster) 〇Keita Yaginuma, Kensaku Matsunami, Laure Descamps, Alexander Ryckaert, Thomas De Beer
  14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18–21 March 2024, Austria Center Vienna, Vienna, Austria (2024) (2024).

国内学会・シンポジウム

• "Integration of Mechanistic and Data-Driven Modeling for Advanced Manufacturing Process Design: Focus on Powder-Based Pharmaceutical Manufacturing"
  (Poster) Kensaku Matsunami
  2024 AIChE Annual Meeting, 27–31 October 2024, San Diego Convention Center/Hilton San Diego Bayfront, San Diego, USA (2024).