研究業績

国際学会

2024年

• "Mechanistic and data-driven models for tablet dissolution to identify key parameters in continuous direct compression"
  (Poster) 〇Kensaku Matsunami, Alexander Ryckaert, Remco Mariën, Bram Bekaert, Valérie Vanhoorne, Thomas De Beer, Chris Vervaet, Ashish Kumar
  14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18–21 March 2024, Austria Center Vienna, Vienna, Austria (2024).
• "Novel approach integrated T-shaped partial least squares regression and transfer learning for tableting scale up"
  (Poster) 〇Keita Yaginuma, Kensaku Matsunami, Laure Descamps, Alexander Ryckaert, Thomas De Beer
  14th World Meeting on Pharmaceutics, Biopharmaceutics and Pharmaceutical Technology, 18–21 March 2024, Austria Center Vienna, Vienna, Austria (2024) (2024).

2023年

• "Uncertainty analysis of hybrid modeling: A case study of partial least squares and population balance model in continuous twin-screw wet granulation"
  (Oral) 〇Kensaku Matsunami, Ana Alejandra Barrera Jiménez, Thomas De Beer, Ingmar Nopens
  2023 AIChE Annual Meeting, 5–10 November 2023, Hyatt Regency, Orlando, USA (2023).
• "Model-based comparison of dissolution behavior between batch and continuous direct compression manufacturing platforms"
  (Oral) 〇Kensaku Matsunami, Remco Mariën, Valérie Vanhoorne, Thomas De Beer, Chris Vervaet, Ashish Kumar
  2023 AIChE Annual Meeting, 5–10 November 2023, Hyatt Regency, Orlando, USA (2023).

2022年

• "Two-dimensional population balance model for twin-screw wet granulation: Model development and calibration based on particle size distribution and porosity"
  (Oral) 〇Kensaku Matsunami, Ana Alejandra Barrera Jiménez, Michiel Peeters, Michael Ghijs, Daan Van Hauwermeiren, Thomas De Beer, Ingmar Nopens
  2022 AIChE Annual Meeting, 13–18 November 2022, Phoenix, AZ, USA (2022).

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• "In-depth analysis of the impacts of material properties on size distributions in continuous twin-screw wet granulation to construct a generic 1D population balance model"
  (Oral) 〇Kensaku Matsunami, Ana Alejandra Barrera Jiménez, Michiel Peeters, Daan Van Hauwermeiren, Thomas De Beer, Ingmar Nopens
  2022 AIChE Annual Meeting, 13–18 November 2022, Phoenix, AZ, USA (2022).

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• "Framework for designing solid drug product manufacturing processes based on economic and quality assessment"
  (Poster) 〇Kensaku Matsunami, Sara Badr, Hirokazu Sugiyama
  The 14th International Symposium on Process Systems Engineering (PSE 2021+), 19–23 June 2022, Kyoto University Clock Tower Centennial Hall, Kyoto, Japan (2022).
• "Towards a generic population balance model for twin-screw wet granulation: from material properties to particle size distribution"
  (Oral) 〇Ana Alejandra Barrera Jiménez, Daan Van Hauwermeiren, Kensaku Matsunami, Michiel Peeters, Thomas De Beer, Ingmar Nopens
  7th International Conference on Population Balance Modelling (PBM 2022), 9–11 May 2022, Lyon, France (2022).

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2020年

• "Surrogate modeling of dissolution behavior toward efficient design of tablet manufacturing processes"
  (Oral) 〇Kensaku Matsunami, Tomohiro Miura, Keita Yaginuma, Shuichi Tanabe, Hirokazu Sugiyama
  2020 AIChE Annual Meeting, 16–20 November 2020, Virtual meeting (2020).

2019年

• "Economic evaluation tool for holistic design of solid drug product manufacturing processes considering continuous technology"
  (Oral) 〇Kensaku Matsunami, Fabian Sternal, Keita Yaginuma, Shuichi Tanabe, Hiroshi Nakagawa, Hirokazu Sugiyama
  2019 AIChE Annual Meeting, 10–15 November 2019, Hyatt Regency, Orlando, U.S.A. (2019).
• "Holistic and model-based design of oral drug manufacturing processes considering uncertainty in clinical development"
  (Oral) 〇Kensaku Matsunami, Hirokazu Sugiyama
  The 8th International Symposium on Design, Operation, and Control of Chemical Processes (PSE Asia 2019), 13–16 January 2019, Chulalongkorn University, Bangkok, Thailand (2019).

2018年

• "Economic evaluation of batch and continuous manufacturing technologies for solid drug products during clinical development"
  (Oral) 〇Kensaku Matsunami, Shuichi Tanabe, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
  13th International Symposium on Process Systems Engineering (PSE 2018), 1–5 July 2018, Manchester Grand Hyatt, San Diego, U.S.A. (2018).
• "Industrial scale experiments towards the development of process evaluation models for continuous pharmaceutical tablet manufacturing"
  (Poster) 〇Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Masahiko Hirao, Hirokazu Sugiyama
  28th European Symposium on Computer-Aided Process Engineering (ESCAPE-28), 10–13 June 2018, the Congress Graz, Graz, Austria (2018).

2017年

• "Large-scale experimental comparison of batch and continuous technologies for pharmaceutical tablet manufacturing"
  (Oral) 〇Kensaku Matsunami, Takuya Nagato, Koji Hasegawa, Masahiko Hirao, Hirokazu Sugiyama
  2017 AIChE Annual Meeting, 29 October–3 November 2017, Minneapolis Convention Center, Minneapolis, U.S.A. (2017).
• "Process systems engineering approaches for drug product manufacturing: from tablets to injectables"
  (Poster) 〇Hirokazu Sugiyama, Kensaku Matsunami, Keisho Yabuta
  27th European Symposium on Computer-Aided Process Engineering (ESCAPE-27), 1–5 October 2017, Fira de Barcelona, Barcelona, Spain (2017).

2016年

• "Selection support methodology between batch and continuous technologies for pharmaceutical tablet manufacturing processes"
  (Oral) 〇Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
  2016 AIChE Annual Meeting, 13–18 November 2016, Hilton San Francisco Union Square, San Francisco, U.S.A. (2016).

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• "Design method for pharmaceutical tablet production considering batch & continuous technologies"
  (Oral) 〇Kensaku Matsunami, Takuya Miyano, Hiroaki Arai, Hiroshi Nakagawa, Masahiko Hirao, Hirokazu Sugiyama
  The 7th International Symposium on Design, Operation & Control of Chemical Processes (PSE Asia 2016), 24–27 July 2016, The University of Tokyo, Tokyo, Japan (2016).

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